Shoulder
Frozen Shoulder & Rotator Cuff Pain
Frozen shoulder (adhesive capsulitis) is the condition with the most published data outside the knee. The joint capsule becomes inflamed and thickened, and abnormal new vessels develop at the rotator interval and axillary recess — the areas that hurt most at night and at end range of motion. Frozen shoulder often improves on its own over one to three years, but that is a long time to live with severe pain. Embolization aims to shorten the painful phase so physical therapy can restore motion.
The same approach is used for rotator cuff tendinopathy and shoulder impingement that has not responded to therapy or injections[1,9,10].
Typical symptoms
- Deep shoulder pain, worse at night
- Loss of motion — reaching overhead or behind the back
- Pain that persists despite therapy or steroid injection

What the studies show
- A 2026 systematic review and meta-analysis (12 studies, 329 shoulders) found large gains in external rotation and shoulder function scores at 3–6 months, with 100% technical success and no severe adverse events[5].
- In the largest single series (118 patients), average pain fell from 7.8 to 2.2 out of 10 at six months, forward flexion improved from about 90° to 143°, and 89.8% reported improvement at one year[6].
- A 2026 comparative study found embolization and arthroscopic capsular release produced similar results at six months[7].

